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For decades, wakefulness medicine has largely focused on indirect stimulation. Drugs like Modafinil and Solriamfetol…
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Modern fatigue has two very different treatment cultures. One is pharmaceutical: targeted, prescription-based, and built…
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What is the role of eugeroics in depression? For many patients with depression, improvement is…
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Pitolisant is one of the most pharmacologically unique wakefulness-promoting medications currently available. Unlike traditional stimulants,…
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Solriamfetol is a relatively new wakefulness-promoting medication used to treat excessive daytime sleepiness associated with…
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Shift work keeps modern societies running—healthcare, transportation, security—but it comes at a biological cost. When…
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The use of Modafinil for ADHD sits in a gray zone between clinical science and…
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Wakefulness is not simply the absence of sleep. It is a carefully regulated neurochemical state…
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Peak mental performance rarely comes from a single trick. Instead, it emerges from a constellation…
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Curiosity about cognitive enhancers has grown steadily over the last decade. Alongside prescription wakefulness agents…